Simplify your single-cell sample prep with the Singulator™ Platform

Stop stressing over unreliable solid tissue dissociation

It is often said that your data is only as good as your starting sample.

For trusted single-cell genomics data, you must begin with high-quality suspensions of viable cells or intact nuclei. Don’t let the variability of manual dissociation methods compromise your work. Automating this process saves time and provides consistent, reliable results every time.

Meet the Singulator™ Platform:

A “set it and forget it” automated system carefully designed to overcome these challenges.

Utilizing precise instrumentation and user-friendly software, the Singulator™ Platform delivers high-quality single cells and nuclei, giving you dependable outputs for your genomic analyses in just minutes.

Uncompromising reproducibility and precision

The Singulator™ Platform consistently produces high-quality results demonstrated in over 80 tissue types. From input amounts as small as 2 mg to customizable protocols, our automated solid tissue dissociation instrument handles it quickly and with little-to-no clean-up.

“Partnered with S2 Genomics, utilizing their Singulator instrument to enhance throughput and consistency in nuclei preparation. Over the past year, more than 400 samples have been processed with the Singulator at SAIL for snRNAseq, snATAC, Multiome, DLP+ and Mission Bio Tapestry.”

“We have worked with jelly fish in the past. Samples performed bad in ATAC-seq and HiC…. now we are trying S2 Genomics nuclei isolation system and seems we got a good library…”

“I’ve observed how the S2 Genomics Singulator 200 revolutionized our tissue processing workflow….Whether we handle fresh, frozen, OCT-preserved, or FFPE tissues, the Singulator consistently provides high-quality samples with minimal manual intervention…Overall, the Singulator has become an indispensable tool for our single-cell genomics studies, with downstream sequencing protocols confirming its reliability.”

“S2 Singulator Support provided invaluable assistance, ensuring our team was always equipped to maximize productivity with the Singulator Platform. Using the Singulator Platform streamlined our workflow incredibly by delivering us fast results. The recorded experiment videos are a delightful feature that we all thoroughly enjoy!”

“The Singulator is so easy to use. I will never go back to manual methods again.…”

“The workflow is fast, efficient and can be applicable for high-throughput clinical and translational research.”

"A new chapter in our lab's #singlecell journey has begun! Starting in 2023, our isolation protocols will include S2 Genomics's Singulator 100 instrument."